Membrane hemocathartique en fibres creuses a base de polysulfone et procédé de production

Polysulfon Hohlfasermembran zur Blutreinigung und Verfahren zu ihrer Herstellung

Polysulfone type hollow fiber membrane for purifying blood and process for producing the same

Abstract

Provided are a polysulfone type blood-purifying membrane which is improved in blood compatibility and separation properties and less in polyvinyl pyrrolidone eluting in the internal surface of the hollow fiber membrane, as well as a process for producing the same. Constitution • A polysulfone type hollow fiber membrane for purifying blood in which membrane a selective separation layer exists on the internal surface side of the hollow fiber membrane and which membrane contains polyvinyl pyrrolidone, wherein the polyvinyl pyrrolidone is contained in a proportion of 1 to 10% by weight, 5 to 50% of said polyvinyl pyrrolidone is soluble in water, and the concentration of the polyvinyl pyrrolidone on the internal surface of the hollow fiber membrane is in the range of 30% to 45%; • A process for producing a polysulfone type hollow fiber membrane for purifying blood, which comprises subjecting a polymer solution comprising a polysulfone type polymer and polyvinyl pyrrolidone to extrusion at a viscosity of 1,500 to 6,000 mPa·s, and to spinning at a draft ratio of 1.1 to 1.9 and at a linear extrusion velocity of not more than 90 m/min.; • A process for producing a polysulfone type hollow fiber membrane for purifying blood, which comprises spinning a hollow fiber membrane using a polymer solution which comprises a polysulfone type polymer and polyvinyl pyrrolidone and thereafter insolubilizing a portion of the polyvinyl pyrrolidone, if necessary, prior to the insolubilization of a portion of the polyvinyl pyrrolidone, it is extracted and removed by washing with a solvent.

Claims

Description

Topics

Download Full PDF Version (Non-Commercial Use)

Patent Citations (14)

    Publication numberPublication dateAssigneeTitle
    EP-0168783-A1January 22, 1986Fresenius AGAsymmetrische mikroporöse Hohlfaser für die Hämodialyse sowie Verfahren zu ihrer Herstellung
    EP-0509663-A1October 21, 1992Toray Industries, Inc.Dialyse Modul mit selektiv-durchlässiger Polysulfon-Hohlfasermembran und Verfahren zur Herstellung
    EP-0550798-A1July 14, 1993Kawasumi Laboratories, Inc., Fresenius-Kawasumi Co., Ltd., Fresenius AGHohlfasermembran auf Basis von Polysulfon
    EP-0750936-A1January 02, 1997Toray Industries, Inc.Permselektive Membranen und Verfahren zu ihrer Herstellung
    JP-H04300636-AOctober 23, 1992Toray Ind IncPolysulfone-based permselective hollow yarn membrane and its manufacture
    JP-H0554373-B2August 12, 1993Fresenius Ag
    JP-H06165926-AJune 14, 1994Kuraray Co Ltd, 株式会社クラレポリスルホン系中空繊維膜とその製造方法
    JP-S61238306-AOctober 23, 1986Toray Ind IncPreparation of semipermeable membrane made of polysulfone resin
    JP-S6397205-AApril 27, 1988Toray Ind IncTreatment of polysulfone resin semipermeable membrane
    JP-S6397634-AApril 28, 1988Toray Ind IncHydrophilic membrane and its production
    JP-S6397666-AApril 28, 1988Toray Ind IncLow-temperature soluble type stock solution and production thereof
    US-5232597-AAugust 03, 1993Kanegafuchi Kagaku Kogyo Kabushiki KaishaPolysulfone porous hollow fiber
    US-5232601-AAugust 03, 1993W. R. Grace & Co.-Conn.High flux hollow fiber membrane
    US-5340480-AAugust 23, 1994Kuraray Co., Ltd.Polysulfone-based hollow fiber membrane and process for manufacturing the same

NO-Patent Citations (0)

    Title

Cited By (2)

    Publication numberPublication dateAssigneeTitle
    CN-104689729-AJune 10, 2015广州市恩德氏医疗制品实业有限公司Polysulfon group and cellulose acetate blended hollow fiber membrane fluid, preparing method thereof and hollow fiber membrane made from the same
    CN-104689729-BJanuary 11, 2017广州市恩德氏医疗制品实业有限公司聚砜族与醋酸纤维素混纺中空纤维膜液和制备方法及其制成的中空纤维膜